Aravinda M de Silva Selected Research

Infections

5/2024	Envelope-dimer epitope-like broadly protective antibodies against dengue in children following natural infection and vaccination.
11/2023	Natural infection by Zika virus but not DNA vaccination consistently elicits antibodies that compete with two potently neutralising monoclonal antibodies targeting distinct epitopes.
1/2023	Structure and neutralization mechanism of a human antibody targeting a complex Epitope on Zika virus.
1/2023	Antibody Immunity to Zika Virus among Young Children in a Flavivirus-Endemic Area in Nicaragua.
1/2022	Ethnoracial Disparities in SARS-CoV-2 Seroprevalence in a Large Cohort of Individuals in Central North Carolina from April to December 2020.
12/2021	A Novel Antigenic Site Spanning Domains I and III of the Zika Virus Envelope Glycoprotein Is the Target of Strongly Neutralizing Human Monoclonal Antibodies.
11/2021	Natural immunogenic properties of bioinformatically predicted linear B-cell epitopes of dengue envelope and pre-membrane proteins.
6/2021	Evaluation of a new point-of-care test to determine prior dengue infection for potential use in pre-vaccination screening.
1/2021	Dengue vaccine breakthrough infections reveal properties of neutralizing antibodies linked to protection.
1/2021	Defining levels of dengue virus serotype-specific neutralizing antibodies induced by a live attenuated tetravalent dengue vaccine (TAK-003).

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Aravinda M de Silva Research Topics

Disease

55	Infections 05/2024 - 06/2007
42	Dengue (Dengue Fever) 05/2024 - 03/2010
10	COVID-19 06/2023 - 01/2020
10	Severe Dengue 01/2017 - 09/2010
7	Zika Virus Infection 01/2020 - 01/2017
7	Coinfection 05/2017 - 09/2009
4	Yellow Fever 01/2018 - 02/2017
3	Virus Diseases (Viral Diseases) 11/2020 - 10/2014
3	Flavivirus Infections 01/2019 - 12/2005
3	Lyme Disease (Disease, Lyme) 06/2007 - 02/2003
2	Convalescence 01/2018 - 01/2017
1	Severe Acute Respiratory Syndrome 01/2022
1	Common Cold 05/2021
1	Communicable Diseases (Infectious Diseases) 01/2021
1	Breakthrough Infections 01/2021
1	Japanese Encephalitis 01/2018
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2018
1	Viremia 01/2018
1	Hepatitis B 01/2018
1	Cytokine Release Syndrome 07/2015
1	Fever (Fevers) 02/2015
1	Human Influenza (Influenza) 02/2014
1	Shock 03/2012
1	Arthritis (Polyarthritis) 06/2007
1	West Nile Fever 12/2005
1	Venezuelan Equine Encephalomyelitis 09/2003

Drug/Important Bio-Agent (IBA)

38	AntibodiesIBA 05/2024 - 12/2005
34	Neutralizing AntibodiesIBA 06/2023 - 03/2010
29	VaccinesIBA 05/2024 - 02/2003
27	EpitopesIBA 05/2024 - 09/2009
16	Proteins (Proteins, Gene)FDA Link 05/2024 - 12/2005
13	Monoclonal AntibodiesIBA 11/2023 - 03/2010
9	Dengue VaccinesIBA 03/2024 - 01/2012
7	Immunoglobulin G (IgG)IBA 01/2023 - 10/2016
6	AntigensIBA 01/2022 - 06/2013
6	Immune Sera (Antisera)IBA 11/2021 - 01/2012
4	Blocking AntibodiesIBA 01/2018 - 03/2012
4	CytokinesIBA 01/2018 - 03/2012
4	Fc Receptors (Fc Receptor)IBA 01/2016 - 06/2011
3	Subunit VaccinesIBA 01/2022 - 10/2016
3	Glycoproteins (Glycoprotein)IBA 12/2021 - 01/2012
3	Peptides (Polypeptides)IBA 11/2021 - 12/2017
3	Attenuated VaccinesIBA 01/2018 - 01/2017
3	Broadly Neutralizing AntibodiesIBA 05/2017 - 02/2015
2	ImmunosorbentsIBA 11/2021 - 01/2018
2	EnzymesIBA 11/2021 - 01/2018
2	Membrane Proteins (Integral Membrane Proteins)IBA 11/2021 - 06/2007
2	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 01/2017 - 08/2015
2	OspA proteinIBA 09/2003 - 02/2003
1	DNA (Deoxyribonucleic Acid)IBA 11/2023
1	B-Lymphocyte Epitopes (B-Cell Epitope)IBA 11/2021
1	Immunoglobulins (Immunoglobulin)IBA 06/2021
1	Viral RNAIBA 11/2020
1	Virus-Like Particle VaccinesIBA 01/2018
1	difluprednate FDA Link 01/2018
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 10/2016
1	Immunoglobulin M (IgM)IBA 10/2016
1	Syk KinaseIBA 07/2015
1	InflammasomesIBA 01/2015
1	Viral AntigensIBA 10/2014
1	Immunoglobulin Fab FragmentsIBA 10/2014

Therapy/Procedure

4	Therapeutics 06/2023 - 12/2005